Abstract
This article analyzes the literary sources of the use of genetic methods in animal husbandry. In particular, the use of genomic (marker) breeding is a technology that allows improving the gene pool of farm animal populations using information about DNA markers. The results of the research of the Department of Animal Husbandry and Aquaculture Management named after M.N. Lushchikhin of K.I.Scriabin KNAU are presented. The conducted literature analysis showed that genomic assessment of the breeding value of farm animals is widely used around the world, but is still not used in Kyrgyzstan. In recent years, the world's breeding progress in animal husbandry has been based on genomic selection. This determined the relevance of the topic under study. The purpose and objectives of our research was the study and analysis of literary sources, genomic technologies in the breeding of farm animals. The results of genotyping for 12 microsatellite markers recommended by the International Society of Animal Genetics (ISAG, International Society for Animal Genetics) are presented: McM042, INRA006, McM527, ETH152, CSRD247, OarFCB20, INRA172, INRA063, MAF065, MAF214, INRA005, INRA023, – and the gender-specific marker AMEL. The results of the study showed that sheep of the Kyrgyz mountain merino breed bred in the state farm "Orgochor" allow us to conclude about its significant genetic diversity and the need to control the parameters of the genetic structure of subpopulations
Keywords
References
[1] Bekturov, A.B., Isakova, Zh.T., Chortonbaev, T.D., Kipen, V.N., Mukeeva, S.B., Shergaziev, U.A., & Aitbaev, K.A. (2023). Study of genetic diversity in the Kyrgyz mountain merino population using microsatellite loci. Genetics, 59(1), 89-96. doi: 10.31857/S001667582301006X.
[2] Chebodaev, D.V., Bekturov, A.B., Turdubaev, T.Zh., & Chortonbaev, T.Zh. (2016). Creation of the Issyk-Kul intrabreed zonal type of sheep of the Kyrgyz mountain merino breed based on the Orgochor state breeding farm. Bulletin of KNAU named after K.I. Skryabin, 3(39), 102-105.
[3] Chortonbaev, T.Zh., Bekturov, A.B., Shergaziev, U.A., & others. (2022). Use of molecular-genetic research methods and creation of information resources for intensifying sheep breeding in the Kyrgyz Republic (Interim report on research work for 2022). Bishkek.
[4] Denisova, T.E., Selionova, M.I., & Gladyr, E.A.. (2016). Microsatellite variability in sheep breeds raised in Russia. Agricultural Biology, 51(6), 801-810.
[5] Gubarev, E.V. (2022). Use of genetic methods in the selection of agricultural animals. In Biology and biotechnology in the service of animal and human health protection: Proceedings of the National scientific-practical conference of young scientists, graduate students, and students (pp. 180-185). Moscow: Agricultural Technologies.
[6] Haley, C.S., & Visscher, P.M. (1998). Strategies to utilize marker-quantitative trait loci associations. Journal of Dairy Science, 81(2), 85-97. doi: 10.3168/jds.S0022-0302(98)70157-2.
[7] Ilkiv, N. (2022). Cattle genetics: New opportunities. Effective Livestock Farming, 3(178), 62-71.
[8] Kapitonova, E.D. (2022). Current stage of genomic selection development. In International forum of young researchers: Proceedings of the III International scientific-practical conference (pp. 334-338). Petrozavodsk: New Science International Research Partnership Center.
[9] Law of the Kyrgyz Republic No. 133 "On Breeding in Livestock of the Kyrgyz Republic". (2009, April). Retrieved from http://cbd.minjust.gov.kg/act/view/ru-ru/202519?cl=ru-ru.
[10] Lysenko, Yu. (2021). Genomic selection: Present and future of livestock farming. Retrieved from https://www.agroyug.ru/news/id-33102.
[11] Marzanov, N.S., Devrishov, D.A., & Feizullaev, F.R. (2020). Immunological, genetic, and biological markers in sheep and goat breeding. In Molecular-genetic technologies for analyzing gene expression of productivity and disease resistance in animals: Proceedings of the II International scientific-practical conference (pp. 249-258). Moscow: Agricultural Technologies.
[12] Nurgaziev, R.Z., Chortonbaev, T.Dzh., Azhibekov, A.S., & Bekturov, A.B. (2015). Patent for breeding achievement No. 50: "Issyk-Kul intrabreed zonal type of Kyrgyz mountain merino sheep" (Merino sheep). Intellectual Property. Official Bulletin, 11(199), 67-68.
[13] Shergaziev, U.A., & Atakulov, A.K. (n.d.). Amplification of milk production genes in cows during repeated oogenesis at heifer age. Retrieved from https://elibrary.ru/item.asp?id=25106304.
[14] Szumiec, A. (2018). Application of 11 STR markers for the evaluation of genetic variation in sheep. ICAR Technical Series, 23, 141-145.
[15] Zafar, I. (2014). Genetic diversity analysis of Kail sheep by using microsatellite markers. The Journal of Animal and Plant Sciences, 24(5), 1329-1333.