Abstract
This article is dedicated to the study of the macroscopic and histological structure of the thymus, lymph nodes, and spleen in clinically healthy sheep. The objects of the morphological study were pieces of lymphoid organs: thymus, lymph nodes, and spleens from sheep aged 2 to 2.5 years. Macroscopically, the thymus in sheep is divided into paired cervical and unpaired thoracic parts. Histologically, the lobules of the thymus consist of cortex and medulla, as well as Hassall's corpuscles. At the age of 2 to 2.5 years, the thymus is subject to age-related involution. Macroscopically, lymph nodes have round, oval, elongated, and triangular shapes, while histologically, they consist of a capsule with trabeculae, cortex, and medulla. The cortex comprises B-zones and T-zones. The spleen is an unpaired organ with an oval or triangular shape and a firm consistency. The spleen consists of red and white pulp. The white pulp is represented by lymphoid tissue, which consists of lymphoid follicles (B-zone) and periarteriolar aggregates (T-zone). In clinically healthy sheep, the lobules of the thymus, T-zones, and B-zones of the lymph nodes and spleen can exist in various morphofunctional states, with a predominance of lymphoid follicles in a resting state. The relatively normal structure of the thymic lobules, T-zones, and B-zones of the lymph nodes and spleen can serve as a reference when studying these organs in cases of infectious, invasive, neoplastic diseases, and immunodeficiencies in sheep
Keywords
References
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